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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC16
All Species:
38.79
Human Site:
S216
Identified Species:
56.89
UniProt:
Q13042
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13042
NP_001072113.1
620
71656
S216
L
K
K
Y
N
K
P
S
E
T
V
I
P
E
S
Chimpanzee
Pan troglodytes
XP_001141335
657
75449
S253
L
K
K
Y
N
K
P
S
E
T
V
I
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001089625
620
71585
S216
L
K
K
Y
N
K
P
S
E
T
V
I
P
E
S
Dog
Lupus familis
XP_848577
620
71476
S216
L
K
K
Y
N
K
P
S
E
T
V
L
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R349
620
71442
S216
L
K
K
Y
N
K
P
S
E
T
V
I
P
E
S
Rat
Rattus norvegicus
NP_001019915
620
71343
S216
L
K
K
Y
N
K
P
S
E
T
V
I
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513048
324
37070
Chicken
Gallus gallus
NP_001006265
624
72618
S218
L
K
K
Y
N
K
P
S
E
T
L
I
P
E
S
Frog
Xenopus laevis
NP_001087093
621
71792
S214
L
K
K
Y
N
K
P
S
E
T
L
I
P
E
S
Zebra Danio
Brachydanio rerio
NP_001032466
616
70436
S217
L
K
K
Y
N
K
P
S
E
M
V
V
P
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623316
640
73022
T226
Y
K
K
Q
V
L
A
T
C
S
V
M
G
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203133
551
62760
R168
L
E
D
L
E
F
V
R
S
L
Y
Q
S
I
L
Poplar Tree
Populus trichocarpa
XP_002331799
542
62607
A159
W
Y
K
A
A
I
K
A
D
P
L
C
Y
E
A
Maize
Zea mays
NP_001141501
580
66070
V196
R
Q
W
Y
K
A
A
V
K
A
D
P
L
C
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565188
543
61743
K158
Q
W
Y
K
A
A
I
K
A
D
P
L
C
Y
E
Baker's Yeast
Sacchar. cerevisiae
P09798
840
94974
T447
Y
I
N
T
E
D
I
T
K
S
N
E
I
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
99.3
97.9
N.A.
95.4
95.9
N.A.
48.2
91.5
88.8
79.1
N.A.
N.A.
49.6
N.A.
49
Protein Similarity:
100
94.3
99.6
98.5
N.A.
97.9
98
N.A.
50.1
95.8
95.8
87.9
N.A.
N.A.
68.1
N.A.
66.7
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
0
93.3
93.3
73.3
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
86.6
N.A.
N.A.
40
N.A.
13.3
Percent
Protein Identity:
35.8
36.9
N.A.
38.2
23.8
N.A.
Protein Similarity:
52.1
54.6
N.A.
54.3
41.5
N.A.
P-Site Identity:
13.3
6.6
N.A.
0
0
N.A.
P-Site Similarity:
40
20
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
13
13
13
7
7
7
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
7
7
7
0
% C
% Asp:
0
0
7
0
0
7
0
0
7
7
7
0
0
7
0
% D
% Glu:
0
7
0
0
13
0
0
0
57
0
0
7
0
50
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
13
0
0
0
0
44
7
7
7
% I
% Lys:
0
63
69
7
7
57
7
7
13
0
0
0
0
0
0
% K
% Leu:
63
0
0
7
0
7
0
0
0
7
19
13
7
7
13
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
0
7
0
57
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
57
0
0
7
7
7
57
0
0
% P
% Gln:
7
7
0
7
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
57
7
13
0
0
7
0
50
% S
% Thr:
0
0
0
7
0
0
0
13
0
50
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
7
7
0
0
50
7
0
7
0
% V
% Trp:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
7
7
63
0
0
0
0
0
0
7
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _